Review



rat anti mouse il 6ra ab  (Bio X Cell)


Bioz Verified Symbol Bio X Cell is a verified supplier
Bioz Manufacturer Symbol Bio X Cell manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 98
      Buy from Supplier

    Structured Review

    Bio X Cell rat anti mouse il 6ra ab
    FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse <t>IL-6Ra</t> Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.
    Rat Anti Mouse Il 6ra Ab, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 98/100, based on 730 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+anti+mouse+il+6ra+ab/pm30617223-101-29-38?v=Bio+X+Cell
    Average 98 stars, based on 730 article reviews
    rat anti mouse il 6ra ab - by Bioz Stars, 2026-06
    98/100 stars

    Images

    1) Product Images from "IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1."

    Article Title: IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    doi: 10.4049/jimmunol.1800717

    FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse IL-6Ra Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.
    Figure Legend Snippet: FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse IL-6Ra Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.

    Techniques Used: In Vivo, Injection, Expressing, Virus, Infection, Control, Cytometry, Comparison



    Similar Products

    rat anti mouse il 6ra ab  (Bio X Cell)
    98
    Bio X Cell rat anti mouse il 6ra ab
    FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse <t>IL-6Ra</t> Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.
    Rat Anti Mouse Il 6ra Ab, supplied by Bio X Cell, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+anti+mouse+il+6ra+ab/pm30617223-101-29-38?v=Bio+X+Cell
    Average 98 stars, based on 1 article reviews
    rat anti mouse il 6ra ab - by Bioz Stars, 2026-06
    98/100 stars
    		  Buy from Supplier

    Image Search Results


    FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse IL-6Ra Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: IL-6 Signaling Blockade during CD40-Mediated Immune Activation Favors Antitumor Factors by Reducing TGF-β, Collagen Type I, and PD-L1/PD-1.

    doi: 10.4049/jimmunol.1800717

    Figure Lengend Snippet: FIGURE 7. Effect of LOAd viruses in vivo. (A) C57BL6/J mice (n = 10 per group) were injected with syngeneic B16 melanoma expressing human CD46 to enable virus infection. At day 5, the tumor was visible under the skin, and the mice were treated by s.c. injection in the tumor area with a LOAd virus expressing murine TMZ-CD40L (mLOAd700; 1 3 109 infection particles per mouse in 50 ml) and/or a rat anti-mouse IL-6Ra Ab (0.5 mg/mouse in 50 ml) or treated with NaCl control. The mice were treated twice a week, six injections in total. Survival was determined by log-rank test, and mLOAd700 was significantly different from control (p = 0.0145). (B) At day 13 (1 d after third treatment), five mice per group were sacrificed, and the tumors were analyzed for immune cell populations using flow cytometry. Statistical differences were calculated by Kruskal–Wallis (ANOVA) with Dunn multiple comparison test. Statistical significance is indicated with *p , 0.05.

    Article Snippet: A virus expressing murine TMZ-CD40L (mLOAd700) was injected s.c. in the tumor area (1 3 109 infectious particles per mouse in 50 ml) with or without coinjection of a rat anti-mouse IL-6Ra Ab (0.5 mg/mouse in 50 ml; BioXCell, West Lebanon, NH).

    Techniques: In Vivo, Injection, Expressing, Virus, Infection, Control, Cytometry, Comparison